Solid tumours

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Disease

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Study title	Protocol ID	Disease type(s)	Location(s)	Eligibility criteria	Status
A Phase 2 Randomised Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# TBD) in Children with Relapsed, Refractory or Progressive Neuroblastoma	ANBL1821	Solid tumours Neuroblastoma	Queensland Children's HospitalBrisbane	External site	Open
A Phase I Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects with Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma	EZH102	Solid tumours	Children's Hospital at WestmeadSydney Queensland Children's HospitalBrisbane Royal Children's Hospital Melbourne Sydney Children's Hospital		Open
A Phase II Study of Panobinostat in Paediatric, Adolescent and Young Adult Patients with Solid Tumours Including Osteosarcoma, Malignant Rhabdoid Tumour/Atypical Teratoid Rhabdoid Tumours and Neuroblastoma	NORTH / ACCT008	Brain and Spinal Tumours ATRT Solid tumours Neuroblastoma Solid tumours Osteosarcoma	Christchurch HospitalChristchurch, New Zealand John Hunter Children's HospitalNewcastle Monash Children's HospitalMelbourne Queensland Children's HospitalBrisbane Royal Children's Hospital Melbourne Royal Hobart HospitalHobart Starship Children's HospitalAuckland, NZ Sydney Children's Hospital	External site	Open
European Low and Intermediate Risk Neuroblastoma - A SIOPEN Study	LINES	Solid tumours Neuroblastoma	Monash Children's HospitalMelbourne Sydney Children's Hospital	External site	Open
International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma	rEECur; RG_13-277	Solid tumours Ewings sarcoma	Christchurch HospitalChristchurch, New Zealand John Hunter Children's HospitalNewcastle Monash Children's HospitalMelbourne Perth Children's HospitalPerth Queensland Children's HospitalBrisbane Starship Children's HospitalAuckland, NZ Sydney Children's Hospital	External site	Open
National Wilms Tumor Late Effects Study	4941L	Solid tumours Renal/kidney	Perth Children's HospitalPerth		Open
Neuroblastoma Biology Studies	ANBL00B1	Solid tumours Neuroblastoma	Children's Hospital at WestmeadSydney John Hunter Children's HospitalNewcastle Perth Children's HospitalPerth Queensland Children's HospitalBrisbane Royal Children's Hospital Melbourne Sydney Children's Hospital Women and Children's HospitalAdelaide		Open
Open-Label, Dose-Escalation, Phase I/II Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics & Clinical Activity of the MEK Inhibitor Trametinib in children and adolescent subjects with Cancer or Plexiform Neurofibromas & Trametinib	GSK MEK	Solid tumours Other Solid Tumour	Children's Hospital at WestmeadSydney		Open
Solid tumour and leukaemia banking	Tumour Bank	Brain and Spinal Tumours Other Brain and Spinal Tumour Leukaemia Other Leukaemia Lymphoma Other Lymphoma Solid tumours Other Solid Tumour	Queensland Children's HospitalBrisbane		Open